Which polyunsaturated fat is anti-inflammatory?

• A. Omega 3 (ALA)
• B. Omega 6 (LA)
• C. Omega 9
• D. Saturated fats

Answer: (A)

Omega-3 fats are anti-inflammatory. They’re polyunsaturated fatty acids that, when metabolized, lead to the production of EPA and DHA-derived mediators that reduce inflammation and promote resolution, such as resolvins and protectins. They also compete with arachidonic acid for the same enzymes, shifting the balance away from pro-inflammatory prostaglandins and leukotrienes. Plant-based omega-3s like ALA are a form of this, contributing to anti-inflammatory effects, though their conversion to EPA/DHA is limited in the body. The other options don’t fit: omega-6 fats can promote inflammation when dominant, omega-9 is not polyunsaturated, and saturated fats aren’t polyunsaturated and don’t confer the same anti-inflammatory benefits.